Las baterías neuropsicológicas empleadas tradicionalmente para el diagnóstico del deterioro cognitivo (DC) en la esclerosis múltiple son pruebas complejas que conllevan mucho tiempo. The MoCA test is a valid and reliable tool for screening for CI in patients with multiple sclerosis. The optimal cut-off point on the ROC curve was 25-26, yielding 91% sensitivity and 93% specificity. The correlation coefficient between total Brief Neuropsychological Battery and MoCA test scores was 0.82. The MoCA test showed good internal consistency (Cronbach alpha, 0.822) and interobserver and test-retest reliability (intraclass correlation coefficient 0.80 and 0.96, respectively). The prevalence of CI was 21.2% according to findings from the Brief Neuropsychological Battery, and 25% according to the MoCA test. We analysed the reliability (internal consistency, interobserver reliability, and test-retest reliability), construct validity (factor analysis, Pearson correlation coefficient, and coefficient of determination), and criterion validity (ROC curve, sensitivity, specificity, total agreement, positive and negative predictive values, positive and negative likelihood ratios, and Fagan nomogram) of the MoCA test in this population. We recruited 52 patients with multiple sclerosis (61.5% women mean age : 41.7 years). We aimed to evaluate the diagnostic validity and reliability of the Montreal Cognitive Assessment (MoCA) test as a screening tool for CI in patients with multiple sclerosis, as compared against the Brief Neuropsychological Battery. Simpler tests are needed to detect cognitive impairment in daily clinical practice. All rights reserved.The neuropsychological batteries traditionally used for the assessment of cognitive impairment (CI) in patients with multiple sclerosis are complex tests requiring a long time to administer. The MoCA-S1-2 is a short, easy-to-use, and useful test for diagnosing aMCI and mild dementia.Īmnestic mild cognitive impairment Cognitive screening Demencia Dementia Deterioro cognitivo leve amnésico Latin America Latinoamérica Minimental State Examination (MMSE) Montreal Cognitive Assessment (MoCA) Tamizaje cognitivo.Ĭopyright © 2017 Sociedad Española de Neurología. The MoCA-S1-2 showed significantly greater discriminant validity than the MMSE for differentiating aMCI from dementia. The level of education had a great impact on scores: as a result, 2 points were added for patients with less than 8 years of schooling and one point for patients with 8-12 years of schooling (MoCA-S1-2). The optimal cut-off points for aMCI and mild dementia were<21 and<20, respectively, with sensitivity and specificity rates of 75% and 82% for aMCI and 90% and 86% for mild dementia. The MoCA-S was found to be an effective and valid test for detecting aMCI (AUC☐.903) and mild dementia (AUC☐.957) its effectiveness for detecting naMCI was lower (AUC☐.629). The MoCA-S displayed good internal consistency (Cronbach's α: 0.772), high inter-rater reliability (Spearman correlation coefficient: 0.846 P<.01), and high intra-rater reliability (test-retest reliability coefficient: 0.922 P<.001). Mean age and years of schooling were 73☖ and 11±4 years, respectively, with no significant intergroup differences. Participants were evaluated with both the MoCA-S and the Mini-Mental State Examination (MMSE) to determine the discriminant validity of the MoCA-S. To evaluate the psychometric properties and discriminant validity of the MoCA-S in elderly patients in Santiago de Chile.ġ72 individuals were grouped according to their clinical diagnosis based on the Clinical Dementia Rating (CDR) scale as follows: amnestic mild cognitive impairment (aMCI n☒4), non-amnestic MCI (naMCI n☒4), mild dementia (n☒0), and cognitively normal (n☑04). Few studies have validated the Spanish-language version of the Montreal Cognitive Assessment (MoCA-S) test in Latin American populations.
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